Sell H, Dietze-Schroeder D, Eckardt K, Eckel J.
Cytokine secretion by human adipocytes is differentially regulated by adiponectin, AICAR and troglitazone.
Biochemical and Biophysical Research Communications. in press

Sell H, Dietze-Schroeder D, Kaiser U, Eckel J.
MCP-1 is a potential player in the negative crosstalk between adipose tissue and skeletal muscle.
Endocrinology. 2006 Jan 26; Epub ahead of print.[Entrez]

Rakatzi I, Stosik M, Gromke T, Siddle K, Eckel J.
Differential Phosphorylation of IRS-1 and IRS-2 by Insulin- and IGF-I-Receptors
Arch Physiol Biochem. in press

Totary-Jain H, Naveh-Many T, Riahi Y, Kaiser N, Eckel J, Sasson S.
Calreticulin destabilizes GLUT-1 mRNA in vascular endothelial and smooth muscle cells under high glucose conditions
Circ Res. 2005 Nov. 11; 97(10): 1001-8. Epub 2005 Oct. 6 [Entrez]

Uhlig M, Passlack W, Eckel J.
Identification and characterisation of a novel variant in the highly conserved catalytic center of Rab11a.
Eur J med Genet. 2006 Jan-Feb; 49(1): 29-36. [Entrez]

Eckel J.
Insulin Analogs Revisited
Cur Med Chem. in press

Dietze-Schroeder D, Sell H, Uhlig M, Koenen M, Eckel J.
Autocrine action of adiponectin on human fat cells prevents the release of insulin resistance-inducing factors.
Diabetes. 2005 Jul;54(7):2003-11. [Entrez]

Ezenwaka C, Kalloo R, Uhlig M, Schwenk R, Eckel J.
The E23K variant in the Kir6.2 subunit of the ATP-sensitive K+ channel does not augment impaired glucose tolerance in Caribbean subjects with a family history of type 2 diabetes.
J Endocrinol. 2005 Jun;185(3):439-44. [Entrez]

Uhlig M, Passlack W, Eckel J.
Functional role of Rab11 in GLUT4 trafficking in cardiomyocytes.
Mol Cell Endocrinol. 2005 May 12;235(1-2):1-9. Epub 2005 Mar 21. [Entrez]

Alpert E, Gruzman A, Riahi Y, Blejter R, Aharoni P, Weisinger G, Eckel J, Kaiser N, Sasson S.
Delayed autoregulation of glucose transport in vascular endothelial cells.
Diabetologia. 2005 Apr;48(4):752-5. [Entrez]

Dietze D, Ramrath S, Ritzeler O, Tennagels N, Hauner H, Eckel J.
Inhibitor kappaB kinase is involved in the paracrine crosstalk between human fat and muscle cells.
Int J Obes Relat Metab Disord. 2004 Aug;28(8):985-92. . [Entrez]

Sommerfeld MR, Metzger S, Stosik M, Tennagels N, Eckel J.
In vitro phosphorylation of insulin receptor substrate 1 by protein kinase C-zeta: functional analysis and identification of novel phosphorylation sites.
Biochemistry. 2004 May 18;43(19):5888-901. [Entrez]

Ezenwaka CE, Kalloo R, Uhlig M, Eckel J.
Relationship between adiponectin and metabolic variables in Caribbean offspring of patients with type 2 diabetes mellitus.
Horm Metab Res. 2004 Apr;36(4):238-42. [Entrez]

Rakatzi I, Mueller H, Ritzeler O, Tennagels N, Eckel J.
Adiponectin counteracts cytokine- and fatty acid-induced apoptosis in the pancreatic beta-cell line INS-1.
Diabetologia. 2004 Feb;47(2):249-58. Epub 2004 Jan 13. [Entrez]

Rakatzi I, Seipke G, Eckel J.
[LysB3, GluB29] insulin: a novel insulin analog with enhanced beta-cell protective action.
Biochem Biophys Res Commun 2003 Oct 24;310(3):852-63. [Entrez]

Wasner HK, Muller G, Eckel J.
Direct comparison of inositol phosphoglycan with prostaglandylinositol cyclic phosphate, two potential mediators of insulin action.
Exp Clin Endocrinol Diabetes 2003 Sep;111(6):358-63. [Entrez]

Rakatzi I, Ramrath S, Ledwig D, Dransfeld O, Bartels T, Seipke G, Eckel J.
A novel insulin analog with unique properties: LysB3,GluB29 insulin induces prominent activation of insulin receptor substrate 2, but marginal phosphorylation of insulin receptor substrate 1.
Diabetes 2003 Sept;52(9):2227-38. [Entrez]

Schreyer S, Ledwig D, Rakatzi I, Kloting I, Eckel J.
Insulin receptor substrate-4 is expressed in muscle tissue without acting as a substrate for the insulin receptor.
Endocrinology 2003 Apr;144(4):1211-8. [Entrez]

Dietze D, Koenen M, Rohrig K, Horikoshi H, Hauner H, Eckel J.
Impairment of insulin signaling in human skeletal muscle cells by co-culture with human adipocytes.
Diabetes 2002 Aug;51(8):2369-76. [Entrez]

Dransfeld O, Rakatzi I, Sasson S, Eckel J.
Eicosanoids and the regulation of cardiac glucose transport.
Ann N Y Acad Sci. 2002 Jun;967:208-16. [Entrez]

Ledwig D, Muller H, Bischoff H, Eckel J.
Early acarbose treatment ameliorates resistance of insulin-regulated GLUT4 trafficking in obese Zucker rats.
Eur J Pharmacol. 2002 Jun 7;445(1-2):141-8. [Entrez]

Muller H, Deckers K, Eckel J.
The fatty acid translocase (FAT)/CD36 and the glucose transporter GLUT4 are localized in different cellular compartments in rat cardiac muscle.
Biochem Biophys Res Commun. 2002 May 3;293(2):665-9. [Entrez]

Doege H, Bocianski A, Scheepers A, Axer H, Eckel J, Joost HG, Schurmann A.
Characterization of human glucose transporter (GLUT) 11 (encoded by SLC2A11), a novel sugar-transport facilitator specifically expressed in heart and skeletal muscle.
Biochem J. 2001 Oct 15;359(Pt 2):443-9. [Entrez]

Dransfeld O, Rakatzi I, Sasson S, Gruzman A, Schmitt M, Haussinger D, Eckel J.
Eicosanoids participate in the regulation of cardiac glucose transport by contribution to a rearrangement of actin cytoskeletal elements.
Biochem J. 2001 Oct 1;359(Pt 1):47-54. [Entrez]

Rizk NM, Joost HG, Eckel J.
Increased Hypothalamic Expression of the p75 Tumor Necrosis Factor Receptor in New Zealand Obese Mice.
Horm Metab Res. 2001 Sep;33(9):520-4. [Entrez]

Rizk NM, Stammsen D, Preibisch G, Eckel J.
Leptin and tumor necrosis factor-alpha induce the tyrosine phosphorylation of signal transducer and activator of transcription proteins in the hypothalamus of normal rats in vivo.
Endocrinology. 2001 Jul;142(7):3027-32. [Entrez]

Kessler A, Uphues I, Ouwens DM, Till M, Eckel J.
Diversification of cardiac insulin signaling involves the p85alpha/beta subunits of phosphatidylinositol 3-kinase
Am J Physiol Endocrinol Metab. 2001 Jan;280(1):E65-74. [Entrez]

Kessler A, Tomas E, Immler D, Meyer HE, Zorzano A, Eckel J.
Rab11 is associated with GLUT4-containing vesicles and redistributes in response to insulin.
Diabetologia. 2000 Dec;43(12):1518-27. [Entrez]

Eckel J, Till M, Uphues I.
Cardiac insulin resistance is associated with an impaired recruitment of phosphatidylinositol 3-kinase to GLUT4 vesicles.
Int J Obes Relat Metab Disord. 2000 Jun;24 Suppl 2:S120-1. [Entrez]

Dransfeld O, Uphues I, Sasson S, Schurmann A, Joost HG, Eckel J.
Regulation of subcellular distribution of GLUT4 in cardiomyocytes: Rab4A reduces basal glucose transport and augments insulin responsiveness.
Exp Clin Endocrinol Diabetes. 2000;108(1):26-36. [Entrez]

Till M, Ouwens DM, Kessler A, Eckel J.
Molecular mechanisms of contraction-regulated cardiac glucose transport.
Biochem J. 2000 Mar 15;346 Pt 3:841-7. [Entrez]

Kausch C, Hamann A, Uphues I, Niendorf A, Muller-Wieland D, Joost HG, Algenstaedt P, Dreyer M, Rudiger HW, Haring HU, Eckel J, Matthaei S.
Association of impaired phosphatidylinositol 3-kinase activity in GLUT1-containing vesicles with malinsertion of glucose transporters into the plasma membrane of fibroblasts from a patient with severe insulin resistance and clinical features of Werner syndrome.
J Clin Endocrinol Metab. 2000 Feb;85(2):905-18. [Entrez]

Ramrath S, Tritschler HJ, Eckel J.
Stimulation of cardiac glucose transport by thioctic acid and insulin.
Horm Metab Res. 1999 Dec;31(12):632-5. [Entrez]

Sebokova E, Gasperikova D, Ouwens M, Dorrestijn J, Eckel J, Maasen A, Klimes I.
Defect in long-term activation of phosphatidylinositol 3-kinase by insulin in vivo: studies in insulin-resistant hHTg rats.
Endocr Regul. 1999 Jun;33(2):49-54. [Entrez]

Rizk NM, Liu LS, Eckel J.
Hypothalamic expression of neuropeptide-Y in the New Zealand obese mouse.
Int J Obes Relat Metab Disord. 1998 Dec;22(12):1172-7. [Entrez]

Liu LS, Tanaka H, Ishii S, Eckel J.
The new antidiabetic drug MCC-555 acutely sensitizes insulin signaling in isolated cardiomyocytes.
Endocrinology. 1998 Nov;139(11):4531-9. [Entrez]

Hauner H, Rohrig K, Spelleken M, Liu LS, Eckel J.
Development of insulin-responsive glucose uptake and GLUT4 expression in differentiating human adipocyte precursor cells.
Int J Obes Relat Metab Disord. 1998 May;22(5):448-53. [Entrez]

Liu LS, Spelleken M, Rohrig K, Hauner H, Eckel J.
Tumor necrosis factor-alpha acutely inhibits insulin signaling in human adipocytes: implication of the p80 tumor necrosis factor receptor.
Diabetes. 1998 Apr;47(4):515-22. [Entrez]

Kessler A, Muller G, Wied S, Crecelius A, Eckel J.
Signalling pathways of an insulin-mimetic phosphoinositolglycan-peptide in muscle and adipose tissue.
Biochem J. 1998 Feb 15;330 ( Pt 1):277-86. [Entrez]

Gasperikova D, Klimes I, Kolter T, Bohov P, Maassen A, Eckel J, Clandinin MT, Sebokova E.
Glucose transport and insulin signaling in rat muscle and adipose tissue. Effect of lipid availability.
Ann N Y Acad Sci. 1997 Sep 20;827:144-57. [Entrez]

Till M, Kolter T, Eckel J.
Molecular mechanisms of contraction-induced translocation of GLUT4 in isolated cardiomyocytes.
Am J Cardiol. 1997 Aug 4;80(3A):85A-89A. [Entrez]

Muller G, Wied S, Crecelius A, Kessler A, Eckel J.
Phosphoinositolglycan-peptides from yeast potently induce metabolic insulin actions in isolated rat adipocytes, cardiomyocytes, and diaphragms.
Endocrinology. 1997 Aug;138(8):3459-75. [Entrez]

Kolter T, Uphues I, Eckel J.
Molecular analysis of insulin resistance in isolated ventricular cardiomyocytes of obese Zucker rats.
Am J Physiol. 1997 Jul;273(1 Pt 1):E59-67. [Entrez]

Bahr M, Kolter T, Seipke G, Eckel J.
Growth promoting and metabolic activity of the human insulin analogue [GlyA21,ArgB31,ArgB32]insulin (HOE 901) in muscle cells.
Eur J Pharmacol. 1997 Feb 12;320(2-3):259-65. [Entrez]

Eckel J.
Direct effects of glimepiride on protein expression of cardiac glucose transporters.
Horm Metab Res. 1996 Sep;28(9):508-11. [Entrez]

von Holtey M, Csermely P, Niggemann J, Eckel J.
Insulin-induced phosphorylation of a 38 kDa DNA-binding protein in ventricular cardiomyocytes: possible implication of nuclear protein phosphatase activity.
Mol Cell Endocrinol. 1996 Jul 1;120(2):107-14.

Bahr M, Spelleken M, Bock M, von Holtey M, Kiehn R, Eckel J.
Acute and chronic effects of troglitazone (CS-045) on isolated rat ventricular cardiomyocytes.
Diabetologia. 1996 Jul;39(7):766-74.

Uphues I, Chern Y, Eckel J.
Insulin-dependent translocation of the small GTP-binding protein rab3C in cardiac muscle: studies on insulin-resistant Zucker rats.
FEBS Lett. 1995 Dec 18;377(2):109-12.

Uphues I, Kolter T, Goud B, Eckel J.
Failure of insulin-regulated recruitment of the glucose transporter GLUT4 in cardiac muscle of obese Zucker rats is associated with alterations of small-molecular-mass GTP-binding proteins.
Biochem J. 1995 Oct 1;311 ( Pt 1):161-6.

Petersen S, Bahr M, Eckel J.
Insulin-dependent regulation of Glut4 gene expression in ventricular cardiomyocytes: evidence for a direct effect on Glut4 transcription.
Biochem Biophys Res Commun. 1995 Aug 15;213(2):533-40.

Hauner H, Petruschke T, Russ M, Rohrig K, Eckel J.
Effects of tumour necrosis factor alpha (TNF alpha) on glucose transport and lipid metabolism of newly-differentiated human fat cells in cell culture.
Diabetologia. 1995 Jul;38(7):764-71.

Bahr M, von Holtey M, Muller G, Eckel J.
Direct stimulation of myocardial glucose transport and glucose transporter-1 (GLUT1) and GLUT4 protein expression by the sulfonylurea glimepiride.
Endocrinology. 1995 Jun;136(6):2547-53.

Russ M, Eckel J.
Insulin action on cardiac glucose transport: studies on the role of protein kinase C.
Biochim Biophys Acta. 1995 Feb 16;1265(1):73-8.

Wichelhaus A, Russ M, Petersen S, Eckel J.
G protein expression and adenylate cyclase regulation in ventricular cardiomyocytes from STZ-diabetic rats.
Am J Physiol. 1994 Aug;267(2 Pt 2):H548-55.

Uphues I, Kolter T, Goud B, Eckel J.
Insulin-induced translocation of the glucose transporter GLUT4 in cardiac muscle: studies on the role of small-molecular-mass GTP-binding proteins.
Biochem J. 1994 Jul 1;301 ( Pt 1):177-82.

Russ M, Wichelhaus A, Uphues I, Kolter T, Eckel J.
Photoaffinity labelling of cardiac membrane GTP-binding proteins in response to insulin.
Eur J Biochem. 1994 Jan 15;219(1-2):325-30.

Russ M, Reinauer H, Eckel J.
Regulation of cardiac insulin receptor function by guanosine nucleotides.
FEBS Lett. 1993 Feb 8;317(1-2):72-6.

Kolter T, Uphues I, Wichelhaus A, Reinauer H, Eckel J.
Contraction-induced translocation of the glucose transporter Glut4 in isolated ventricular cardiomyocytes.
Biochem Biophys Res Commun. 1992 Dec 15;189(2):1207-14.

Russ M, Reinauer H, Eckel J.
Diabetes-induced decrease in the mRNA coding for sarcoplasmic reticulum Ca(2+)-ATPase in adult rat cardiomyocytes.
Biochem Biophys Res Commun. 1991 Aug 15;178(3):906-12.

Petersen S, Russ M, Reinauer H, Eckel J.
Inverse regulation of glucose transporter Glut4 and G-protein Gs mRNA expression in cardiac myocytes from insulin resistant rats.
FEBS Lett. 1991 Jul 29;286(1-2):1-5.

Eckel J, Asskamp B, Reinauer H.
Induction of insulin resistance in primary cultured adult cardiac myocytes.
Endocrinology. 1991 Jul;129(1):345-52.

Eckel J, Gerlach-Eskuchen E, Reinauer H.
Alpha-adrenoceptor-mediated increase in cytosolic free calcium in isolated cardiac myocytes.
J Mol Cell Cardiol. 1991 May;23(5):617-25.

Eckel J, Gerlach-Eskuchen E, Reinauer H.
G-protein-mediated regulation of the insulin-responsive glucose transporter in isolated cardiac myocytes.
Biochem J. 1990 Dec 15;272(3):691-6.

Eckel J, Reinauer H.
Insulin action on glucose transport in isolated cardiac myocytes: signalling pathways and diabetes-induced alterations.
Biochem Soc Trans. 1990 Dec;18(6):1125-7.

Eckel J, Reinauer H.
Modulation of transmembrane potential of isolated cardiac myocytes by insulin and isoproterenol.
Am J Physiol. 1990 Aug;259(2 Pt 2):H554-9.

Eckel J, Reinauer H.
Involvement of hormone processing in insulin-activated glucose transport by isolated cardiac myocytes.
Biochem J. 1988 Jan 1;249(1):111-6.

Eckel J, Rohn G, Kiesel U, Reinauer H.
Insulin binding and action in isolated cardiocytes from spontaneously diabetic BB rats.
Diabetes Res. 1987 Feb;4(2):79-83.

van Echten G, Eckel J, Reinauer H.
Down-regulation of insulin receptors in the heart: studies on primary cultured adult cardiac myocytes.
Biochim Biophys Acta. 1986 May 29;886(3):468-73.

Eckel J, van Echten G, Reinauer H.
Adult cardiac myocytes in primary culture: cell characteristics and insulin-receptor interaction.
Am J Physiol. 1985 Aug;249(2 Pt 2):H212-21.

Eckel J, Wirdeier A, Herberg L, Reinauer H.
Insulin resistance in the heart: studies on isolated cardiocytes of genetically obese Zucker rats.
Endocrinology. 1985 Apr;116(4):1529-34.

Eckel J, Reinauer H.
Glucose uptake in isolated heart cells: studies on the role of insulin.
Basic Res Cardiol. 1985;80 Suppl 2:103-6.

Eckel J, Reinauer H.
The insulin receptor of adult heart muscle cells.
Basic Res Cardiol. 1985;80 Suppl 1:61-4.

Eckel J, Reinauer H.
Insulin action on cardiac glucose transport. Studies on the role of the sodium pump.
Adv Myocardiol. 1985;6:105-11.

Haring HU, Machicao F, Kirsch D, Rinninger F, Holzl J, Eckel J, Bachmann W.
Protein kinase activity of the insulin receptor from muscle.
FEBS Lett. 1984 Oct 15;176(1):229-34.

Eckel J, Reinauer H.
Effect of EDTA on insulin binding and insulin action in isolated cardiocytes from adult rat. Evidence for a functional role of low-affinity insulin receptors.
Diabetes. 1984 Mar;33(3):214-8.

Eckel J, Reinauer H.
Insulin action on cardiac glucose transport. Studies on the role of the Na+/K+ pump.
Biochim Biophys Acta. 1983 Dec 7;736(1):119-24.

Rosen P, Eckel J, Reinauer H.
Influence of bradykinin on glucose uptake and metabolism studied in isolated cardiac myocytes and isolated perfused rat hearts.
Hoppe Seylers Z Physiol Chem. 1983 Oct;364(10):1431-8.

Eckel J, Reinauer H.
Effects of microtubule-disrupting agents on insulin binding and degradation in isolated cardiocytes from adult rat.
Hoppe Seylers Z Physiol Chem. 1983 Jul;364(7):845-50.

Eckel J, Pandalis G, Reinauer H.
Insulin action on the glucose transport system in isolated cardiocytes from adult rat.
Biochem J. 1983 May 15;212(2):385-92.

Eckel J, Reinauer H.
The fate of insulin in cardiac muscle. Studies on isolated muscle cells from adult rat heart.
Biochem J. 1982 Sep 15;206(3):655-62.

Eckel J, Offermann A, Reinauer H.
Insulin receptors on isolated heart cells: effect of temperature and hydrolytic enzymes.
Basic Res Cardiol. 1982 May-Jun;77(3):323-32.

Eckel J, Reinauer H.
Characteristics of insulin receptors in the heart muscle: binding of insulin to isolated muscle cells from adult rat heart.
Biochim Biophys Acta. 1980 May 22;629(3):510-21.

Eckel J, Reinauer H.
Effect of vinblastine on the insulin-receptor interaction in mammalian heart muscle.
Biochem Biophys Res Commun. 1980 Feb 27;92(4):1403-8.

Eckel J, Rao GS, Rao ML, Breuer H.
Uptake of L-tri-iodothyronine by isolated rat liver cells. A process partially inhibited by metabolic inhibitors; attempts to distinguish between uptake and binding to intracellular proteins.
Biochem J. 1979 Aug 15;182(2):473-91.

Rao ML, Rao GS, Eckel J, Breuer H.
Factors involved in the uptake of corticosterone by rat liver cells.
Biochim Biophys Acta. 1977 Dec 22;500(2):322-32.

Rao GS, Eckel J, Rao ML, Breuer H.
Uptake of thyroid hormone by isolated rat liver cells.
Biochem Biophys Res Commun. 1976 Nov 8;73(1):98-104.